The research is published in Molecular Nutrition & Food Research.
"Green tea is a popular beverage across the world," said Professor Yun Bai from the Third Military Medical University, Chongqing, China. "There has been plenty of scientific attention on its use in helping prevent cardiovascular diseases, but now there is emerging evidence that its chemical properties may impact cellular mechanisms in the brain."
Professor Bai's team focused on the organic chemical EGCG, (epigallocatechin-3 gallate) a key property of green tea. While EGCG is a known anti-oxidant, the team believed it can also have a beneficial effect against age-related degenerative diseases.
"We proposed that EGCG can improve cognitive function by impacting the generation of neuron cells, a process known as neurogenesis," said Bai. "We focused our research on the hippocampus, the part of the brain which processes information from short-term to long-term memory."
"We have shown that the organic chemical EGCG acts directly to increase the production of neural progenitor cells, both in glass tests and in mice," concluded Bai. "This helps us to understand the potential for EGCG, and green tea which contains it, to help combat degenerative diseases and memory loss."
This paper is published as part of a collection of articles bringing together high quality research on the theme of food science and technology with particular relevance to China. Browse free articles from Wiley's food science and technology publications including the Journal of Food Science, Journal of the Science of Food and Agriculture and Molecular Nutrition & Food Research.
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Yanyan Wang, Maoquan Li, Xueqing Xu, Min Song, Huansheng Tao, Yun Bai. Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis. Molecular Nutrition & Food Research, 2012; 56 (8): 1292 DOI: 10.1002/mnfr.201200035
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